venofer dosing calculator

There is in depth information below the form on the method used and on the result provided. Monitor Closely (1)iron sucrose decreases levels of thyroid desiccated by inhibition of GI absorption. Calculation of Iron Deficit - Perinatology.com By clicking send, you acknowledge that you have permission to email the recipient with this information. 2) Koch TA, Myers J, Goodnough LT. (2015) Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations. J Med. Patients with a history of drug allergy or multiple drug allergies may be at increased risk of anaphylactic-type reactions to INFeD. with NDD-CKD or PDD-CKD who are on erythropoietin therapy for iron maintenance treatment, Hemodialysis-dependent chronic kidney disease (HDD-CKD)*, Non-dialysis-dependent chronic kidney disease (NDD-CKD), Peritoneal-dialysis-dependent chronic kidney disease (PDD-CKD), At a dose of 0.5 mg/kg, not to exceed 100 mg per dose, Given undiluted by slow intravenous injection over 5 minutes or diluted in 0.9% NaCl at concentrations of 1 to 2 mg/mL and administered over 5 to 60 minutes, An increase in Hb concentration or a decrease in ESA dose is desired and. FERAHEME vs Venofer (iron sucrose) - Feraheme Observed Hb = the patients current hemoglobin in g/dl. Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. 3) Bayraktar UD, Bayraktar S. (2010) Treatment of iron deficiency anemia associated with gastrointestinal tract diseases. Monitor Closely (1)aluminum hydroxide will decrease the level or effect of iron sucrose by increasing gastric pH. Hemodialysis-dependent: 0.5 mg/kg IV q2weeks for 12 weeks; not to exceed 100 mg/dose, Non-dialysis dependent or peritoneal-dependent (on erythropoietin): 0.5 mg/kg IV q4weeks for 12 weeks; not to exceed 100 mg/dose, sodium sulfate/?magnesium sulfate/potassium chloride, sodium sulfate/potassium sulfate/magnesium sulfate, Serious hypersensitivity reactions reported, including anaphylactic-type reactions, some of which have been life-threatening and fatal, Patients may present with shock, clinically significant hypotension, loss of consciousness, and/or collapse, If hypersensitivity reactions or signs of intolerance occur during administration, stop infusion immediately, Monitor patients for signs and symptoms of hypersensitivity during and after administration for at least 30 minutes and until clinically stable following completion of the infusion, Animal reproduction studies of iron sucrose administered to rats and rabbits during period of organogenesis at elemental iron doses equivalent to maximum recommended human dose based on body surface area revealed no evidence of harm to the fetus; adverse outcomes in pregnancy occur regardless of health of mother or use of medications, Iron deficiency anemia during pregnancy should be treated; untreated IDA in pregnancy is associated with adverse maternal outcomes such as post-partum anemia; adverse pregnancy outcomes associated with IDA include increased risk for preterm delivery and low birth weight, HD-dependent and non-dialysis-dependent CKD: Dilute with up to 100 mL of 0.9% NaCl, PD-dependent CKD: Dilute with up to 250 mL of 0.9% NaCl, Undiluted: Administer by slow IV injection over 2-5 min, Diluted solutions: Administer IV over 15 min, Undiluted: Administer by slow IV injection over 5 minutes, Diluted solutions: Administer IV over 5-60 minutes, Store in original carton at 20-25C (68-77 F); excursions permitted to 15- 30C (59-86F), Syringe: Store at room temperature (25C) or under refrigeration (4C) for up to 7 days, IV infusion: Store at room temperature (25C) for up to 7 days. Venofer (Iron Sucrose Injection): Uses, Dosage, Side Effects - RxList For additional Safety Information, please see Full Prescribing Information. It varies from increases in dietary intake of iron (usually for prophylaxis purposes) to oral, intramuscular or intravenous therapy. Baloxavir may bind to polyvalent cations resulting in decreased absorption. Applies only to oral form of both agents. Applies only to oral form of both agents. Bhowmik D, Modi G, Ray D, Gupta S, Agarwal SK, Tiwari SC, Dash SC. IDA symptoms are often nonspecific and include tiredness, weakness, shortness of breath. Applies only to oral form of both agents. Have resuscitation equipment and personnel trained in the detection and treatment of anaphylactic-type reactions readily available during INFeD administration. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Iron Sucrose - Injection - Alberta Serious - Use Alternative (1)iron sucrose will decrease the level or effect of baloxavir marboxil by cation binding in GI tract. Serum iron, total iron binding capacity (TIBC) and percent saturation of transferrin are other important tests for detecting and monitoring the iron deficient state. Applies only to oral form of both agents. 2. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. The dosage is expressed in terms of mg of elemental iron, with each mL of Feraheme containing 30 mg of elemental iron. INFED- iron dextran injection [Package insert], Hemoglobin iron deficit (mg) = weight (kg) x (14 - Hgb) x (2.145) Note: Hbg (current hemoglobin level) units: (g/dL) Alternatively: Volume of product required (mL) = [weight (kg) x (14 - Hgb) x (2.145)] / C Where C= concentration of elemental iron (mg/ml) in the product being used: Iron dextran: 50 mg/mL. Drug class: Iron products. Minor/Significance Unknown. The recipient will receive more details and instructions to access this offer. Minor/Significance Unknown. Ferric carboxymaltose (Ferinject) for iron-deficiency anaemia Applies only to oral form of both agents. provider for the most current information. Minor/Significance Unknown. 2022 American Regent, Inc.PP-VE-US-0016 (v6.0)1/2022. Copyright 1993-2021 Avoid or Use Alternate Drug. Use Caution/Monitor. When to Use Weight lbs Target hemoglobin g/dL Actual hemoglobin g/dL Iron stores Use 500 mg for adults and children 35 kg; use 15 mg/kg if <35 kg mg Result: Please fill out required fields. Monitor Closely (1)lansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. The Ganzoni equation used by the iron deficiency calculator is the following: Total iron deficit (mg) = Weight in kg x (Target Hb - Actual Hb in g/dL) x 2.4 + Iron stores. Monitor Closely (1)famotidine will decrease the level or effect of iron sucrose by increasing gastric pH. Give each dose as 750mg for a total cumulative dose not to exceed1500mg of ironper course. Applies only to oral form of both agents. Modify Therapy/Monitor Closely. The factor 2.4 comes about from the calculation that the total iron content of hemoglobin is 0.34%, the blood volume accounts for 7% . . Am J Kid Dis 2001; 38 988991. Mean Corpuscular Hemoglobin Concentration (MCHC) Calculator, Red Blood Cell (RBC) Indices Calculator, Iron Deficiency In Pregnancy Calculator. Venofer (iron sucrose injection, USP) For Intravenous Use Only INDICATION AND USAGE Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD). Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. Venofer (iron sucrose) dose calculator | Calculosaurus.com Clinical calculators for obstetrics and gynaecology VTE risk assessment Calculator menu Venofer dose calculator Iron sucrose Not what you were looking for? Each mL contains 20 mg of elemental iron. Perinatology and Obstetrical Calculators The iron deficit calculator is useful as one of the determinations performed before iron replenishment therapy is initiated. Monitor Closely (1)calcium carbonate will decrease the level or effect of iron sucrose by increasing gastric pH. Use Caution/Monitor. Use Caution/Monitor. The Ganzoni equation is: Total iron deficit (mg) = Weight in kg x (Target Hb - Actual Hb in g/dL) x 2.4 + Iron stores In most cases, adult patients require a cumulative dose of elemental iron of at least 1 g. Most commonly, iron replenishment therapy is done intravenously: As total dose (iron-dextran or iron - carboxymaltose); ibuprofen/famotidine will decrease the level or effect of iron sucrose by increasing gastric pH. Studies in monkeys showed concurrent use with calcium, aluminum, or iron caused significantly decreased plasma levels. When iron sucrose was administered at deliberate overdoses to rabbit dams (up to 215 mg/kg/day) marked fetal/placental iron overload was noted. Deferasirox chelates iron. The dosage of Venofer is expressed in mg of elemental iron. Am J Hosp Pharm. Use Caution/Monitor. Use Caution/Monitor. Taking the case of a patient weighing 75 kg (165.3 lbs) with a target hemoglobin value of 13 g/dL (130 g/L or 8.07 mmol/L), an actual hemoglobin of 9.5 g/dL (95 g/L or 5.9 mmol/L) and iron stores of 500 mg, the iron deficit is: Iron deficit = 75 x (13 9.5) x 2.4 + 500 = 1,130 mg. famotidine will decrease the level or effect of iron sucrose by increasing gastric pH. Multiple placebo-controlled, randomized clinical trials have been conducted with IV iron in patients with New York Heart Association class II-III heart failure with an ejection fraction 45% who met criteria . Applies only to oral form of both agents. Either decreases levels of the other by inhibition of GI absorption. Option 2: 200 mg in NS 100 mL administered over 20-30 minutes; may repeat every other day to Avoid or Use Alternate Drug. Studies in monkeys showed concurrent use with calcium, aluminum, or iron caused significantly decreased plasma levels. The usual total treatment course of Venofer is 1000 mg. Venofer treatment may be repeated if iron deficiency reoccurs. Privacy Policy, Use 500 mg for adults and children 35 kg; use 15 mg/kg if <35 kg. Applies only to oral form of both agents. Monitor Closely (1)omeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Applies only to oral form of both agents. For males: LBW = 50 kg + 2.3 kg for each inch of patients height over 5 feet For females: LBW = 45.5 kg + 2.3 kg for each inch of patients height over 5 feet Administration: I. Hemoglobin there are two fields for hemoglobin input, one for the target and another for actual value. Applies only to oral form of both agents. Your doctor will do laboratory tests to monitor your response. Either increases effects of the other by pharmacodynamic synergism. We'll do this entirely for free, as long as the calculator has applications for women's health. Copyright 2014 - 2023 The Calculator .CO |All Rights Reserved|Terms and Conditions of Use, Parenteral Iron Replacement For Iron Deficiency Anemia Calculator, Intravenous Iron Therapy in Patients with Iron Deficiency Anemia: Dosing Considerations, Clinical use of the total dose intravenous infusion of iron dextran, When is high-dose intravenous iron repletion needed? Avoid or Use Alternate Drug. Avoid or Use Alternate Drug. Venofer may reduce the absorption of concomitantly administered oral iron preparations. Treatment of anemia due to iron deficiency. iron sucrose decreases levels of thyroid desiccated by inhibition of GI absorption. In: Koda-Kimble & Young's Applied Therapeutics: The Clinical Use of Drugs. Modify Therapy/Monitor Closely. Most studies have used IV iron sucrose (maximum dose of 200 mg per setting) or ferric carboxymaltose (maximum dose of 1000 mg per week). Use Caution/Monitor. Modify Therapy/Monitor Closely. Use Caution/Monitor. Applies only to oral form of both agents. Venofer may cause clinically significant hypotension. . feasible, Maximum total cumulative iron sucrose dose administered in 14 days is 1000 mg elemental iron. Our dosage calculator can help you with this as well. Applies only to oral form of both agents. Applies only to oral form of both agents. Found in multiple references. PDF IRON PRODUCT CHOICE AND DOSE CALCULATION - Blood Iron sucrose: 20 mg/mL. May increase risk of hypotension. iron sucrose decreases levels of eltrombopag by inhibition of GI absorption. Venofer (iron sucrose) dose, indications, adverse effects - PDR Applies only to oral form of both agents. Each mL contains 20 mg of elemental iron. The iron formulation choice remains for the clinician to make. The incidence of adverse events with the 400- and 500-mg doses administered as a 2-hour . You will have to pay for your IV iron. Venofer [package insert]. Iron Deficiency in Heart Failure - Home - American College of Cardiology Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: vitamin products, other iron-containing products. SIDE EFFECTS: Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. Pasricha SR, Flecknoe-Brown SC, Allen KJ, Gibson PR, McMahon LP, Olynyk JK, Roger SD, Savoia HF, Tampi R, Thomson AR, Wood EM, Robinson KL. 1995 Mar-Apr;11(2):163-8. Do not administer Venofer to patients with evidence of iron overload. Venofer can be given as a maximum of 200mg not more than 3 times per week; doses must be 24 hours apart. Feraheme, when added to intravenous infusion bags containing either 0.9% Sodium Chloride Injection, USP (normal saline), or 5% Dextrose Injection, USP, at concentrations of 2-8 mg elemental iron per mL, should be used immediately but may be stored at controlled room temperature (25C 2C) for up to 4 hours or refrigerated (2-8 C) for up to 48 hours. Total dose iron infusion: safety and efficacy in predialysis patients. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Applies only to oral form of both agents. INFeD is given undiluted at a slow gradual rate not to exceed 50 mg (1 mL) per minute. concentration of elemental iron (mg/ml) in the product being used: This calculator will help pinpoint potential causes of anemia based on an automated flowchart approach. Venofer (Iron Sucrose Injection) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including drug comparison and health resources. Intravenous Injection - PRIOR TO THE FIRST INTRAVENOUS INFeD THERAPEUTIC DOSE, ADMINISTER AN INTRAVENOUS TEST DOSE OF 0.5 ML. Use INFeD only in patients in whom clinical and laboratory investigations have established an iron deficient state not amenable to oral iron therapy. Venofer treatment may be repeated if necessary. You may report side effects to Health Canada at 1-866-234-2345. Iron deficit - equation derivation: Assumptions: -Blood volume = 65 mL/kg -Hemoglobin conc target =14.0 g/dL -Deficits in body stores are ignored. This drug is available at a higher level co-pay. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Use Caution/Monitor. Applies only to oral form of both agents. Applies only to oral form of both agents. Adult Patients with Hemodialysis Dependent-Chronic Kidney Disease (HDD-CKD): Administer Venofer 100 mg undiluted as a slow intravenous injection over 2 to 5 minutes, or as an infusion of 100 mg diluted in a maximum of 100 mL of 0.9% NaCl over a period of at least 15 minutes, per consecutive hemodialysis session. The primary endpoint was the proportion of patients with . )If you are using this medication at home, learn all preparation and usage instructions from your health care professional. Monitor Closely (1)dexlansoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. David McAuley, Pharm.D. Fatal reactions have also occurred in situations where the test dose was tolerated. Monitor Closely (1)iron sucrose decreases levels of levothyroxine by inhibition of GI absorption. Iron Sucrose Monograph for Professionals - Drugs.com Each costs about $0.46 to $0.55 per mg of iron. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvdmVub2Zlci1pcm9uLXN1Y3Jvc2UtMzQyMTYy, View explanations for tiers and Always ask your health care professional for complete information about this product and your specific health needs. Echocardiogram Z Score (NEW)(BETA TESTING) Edinburgh Postnatal Depression Scale. didanosine will decrease the level or effect of iron sucrose by increasing gastric pH. Minor/Significance Unknown.iron sucrose increases levels of calcium carbonate by enhancing GI absorption. 1970;100(7):301303. All you have to do is use the following formula: Liquid\ dose = Dose / Medicine\ concentration Liquid dose = Dose/M edicine concentration. Use Caution/Monitor. Ganzoni Equation for Iron Deficiency Anemia - MDCalc 2010niferex-hytinic-polysaccharide-iron-342160Drugs, You are being redirected to Compare formulary status to other drugs in the same class. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. Monitor Closely (1)deferasirox decreases levels of iron sucrose by inhibition of GI absorption. Use alternatives if available. Serious - Use Alternative (1)iron sucrose decreases levels of oxytetracycline by inhibition of GI absorption. There are four variables, all patient parameters, required in the iron deficiency calculator: The patients weight is used in the Ganzoni equation and also when establishing the iron stores. This topic . This information does not assure that this product is safe, effective, or appropriate for you. Injection: 50 mg/2.5 mL, 100 mg/5 mL, or 200 mg/10 mL (20 mg/mL) in single-dose vials. Venofer Dosing and Administration Separate dosing of tetracyclines from these products. Iron Sucrose Dosage Guide + Max Dose, Adjustments - Drugs.com IV iron sucrose (Venofer) given as divided dosages, and low molecular weight iron dextran (CosmoFer) this can be given as divided dose or as a total dose infusion . Applies only to oral form of both agents. Consult your doctor for more details.Remember that it is best to get your vitamins and minerals from food whenever possible. VENOFER (IRON SUCROSE INJECTION,USP) 100mg ELEMENTAL IRON - DailyMed Suggested regime: Prescribing instructions Prescribing a single/first dose: The two formulas used are presented below: Iron deficit in mg = Weight in kg x (14 - Hb in g/dL) x 2.145 Volume of product required in mL = Iron deficit in mg / C in mg/mL Where C is the concentration of the iron product: 50 mg/mL for Iron dextran; 20 mg/mL for Iron sucrose; 5 mg/mL for Ferric gluconate. Sodium ferric gluconate complex injection [ Ferrlecit ] [package insert] - Elemental iron: 12.5 mg/mL (5 mL). Kumpf VJ, Holland EG. Methods. 10th ed. Minor/Significance Unknown. iron sucrose decreases levels of mycophenolate by inhibition of GI absorption. In the text below the tool there is more information on how the iron deficit is calculated. Applies only to oral form of both agents. Iron supplements, whether administered orally, intramuscular or intravenous, are used to replenish body stores and correct anemia. Information last revised December 2022. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. Monitor Closely (1)ibuprofen/famotidine will decrease the level or effect of iron sucrose by increasing gastric pH. Copyright 1993-2021 Applies only to oral form of both agents. Excessive dosages of Venofer may lead to accumulation of iron in storage sites potentially leading to hemosiderosis. Monitor Closely (1)sodium sulfate/?magnesium sulfate/potassium chloride decreases levels of iron sucrose by inhibition of GI absorption. Applies only to oral form of both agents. Applies only to oral form of both agents. Initial symptoms may include hypotension, syncope, unresponsiveness, cardiac/cardiorespiratory arrest. Venofer treatment may be repeated if necessary. Venofer® (iron sucrose) injection, USP is indicated for the treatment of iron deficiency anemia (IDA) in patients with chronic kidney disease (CKD). Anemia. The cost of Venofer is $145 for a dose of 300 mg and Monoferric is $274 for a dose of 500mg. Drug Dosing in Obesity Reference Table - ClinCalc.com Your list will be saved and can be edited at any time. Iron Deficit - Multi-Calc - GlobalRPH - Medical Calculators, Clinicians Applies only to oral form of both agents. Avoid or Use Alternate Drug. Results: Twelve children (6 females) aged 1.2-14 years (median age 8.9 years) received at least one dose of . . Iron Injection Administration | INJECTAFER HCP Applies only to oral form of both agents. Interaction only with oral iron administration. Use Caution/Monitor. Administer Feraheme as an intravenous infusion in 50-200 mL 0.9% Sodium Chloride Injection, USP or 5% Dextrose Injection, USP over at least 15 minutes. Inspect parenteral drug products visually for the absence of particulate matter and discoloration prior to administration. This drug is available at a higher level co-pay. Dosing Administration & Considerations . Avoid or Use Alternate Drug. These adverse reactions have occurred up to 30 minutes after the administration of Venofer injection. (3) Known hypersensitivity to Venofer. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. Applies only to oral form of both agents. Adverse pregnancy outcomes associated with IDA include increased risk for preterm delivery and low birth weight. 200-800 mg/kg (2-8 mL/kg) every 3-4 weeks. Applies only to oral form of both agents. Administer ciprofloxacin at least 2 hours before or 6 hours after using these products. In this study and another study evaluating a single intravenous dose of iron sucrose containing 500-700 mg of iron in 26 anemic patients on erythropoietin therapy (23 female, 3 male; age range 16-60), approximately 5% of the iron was . Case G. Maintaining iron balance with total-dose infusion of intravenous iron dextran. Minor/Significance Unknown. This site complies with the HONcode standard for trust- worthy health information: verify here. 2.1 . 5. 4)Pasricha SR, Flecknoe-Brown SC, Allen KJ, Gibson PR, McMahon LP, Olynyk JK, Roger SD, Savoia HF, Tampi R, Thomson AR, Wood EM, Robinson KL. cimetidine will decrease the level or effect of iron sucrose by increasing gastric pH. Minor/Significance Unknown. rabeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. esomeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Use Caution/Monitor. One dose IV Iron replacement | Monoferric 3) Auerbach M, Witt D, Toler W, Fierstein M, Lerner RG, Ballard H. (1988) Clinical use of the total dose intravenous infusion of iron dextran. Applies only to oral form of both agents. sodium bicarbonate will decrease the level or effect of iron sucrose by increasing gastric pH. Applies only to oral form of both agents. Serious - Use Alternative (1)iron sucrose decreases levels of ofloxacin by inhibition of GI absorption. Applies only to oral form of both agents. PDF Iron Sucrose: Guidelines for Administration Document Type: Guideline Use Caution/Monitor. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. Coadministration of ciprofloxacin with multivalent cation-containing products may reduce the bioavailability of ciprofloxacin by 90%. MISSED DOSE: It is important to get each dose of this medication as scheduled. Applies only to oral form of both agents. Minor/Significance Unknown. Venofer is given as an infusion into a vein. It should be recognized that iron storage may lag behind the appearance of normal blood morphology.

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